Azoospermia

Azoospermia (Zero Sperm Count) and Male Infertility

No Sperm Doesn’t Mean No Hope

A diagnosis of azoospermia — complete absence of sperm in the ejaculate — can come as a shock. But thanks to advancements in reproductive medicine, fatherhood is still possible for many men with this condition. At Sparsh IVF, we specialize in diagnosing and treating azoospermia with a combination of clinical expertise, microsurgical precision, and compassionate care.

Whether the cause is hormonal, genetic, or structural, our goal is to find the solution that brings you one step closer to fatherhood.

What Is Azoospermia?

Azoospermia is the complete absence of sperm in a man’s semen. It affects about 1% of all men and up to 15% of infertile men. Despite sounding final, it’s a condition that can often be treated or bypassed through assisted reproductive technologies (ART).

There are two main types:

TypeDescriptionTreatment Approach
Obstructive Azoospermia (OA)Sperm is produced but blocked from releaseSurgical retrieval or correction
Non-Obstructive Azoospermia (NOA)Testicles are not producing spermHormonal stimulation or sperm retrieval

Understanding which type of azoospermia you have is the first step to building your fertility plan.

Causes of Azoospermia

Caused by blockages in the reproductive tract:

  • Vas deferens obstruction (e.g., post-vasectomy)
  • Congenital absence of vas deferens (seen in cystic fibrosis carriers)
  • Infections (e.g., mumps, STIs)
  • Trauma or surgery in groin area
  • Ejaculatory duct obstruction

Caused by testicular failure or hormonal issues:

  • Genetic abnormalities (Klinefelter syndrome, Y chromosome microdeletions)
  • Radiation or chemotherapy exposure
  • Hormonal imbalance (low FSH/LH/testosterone)
  • Undescended testes or torsion
  • Chronic illness, substance abuse

Symptoms and Warning Signs

Most men with azoospermia experience no obvious symptoms. It’s usually diagnosed during fertility testing. However, possible indicators may include:

  • Low semen volume or dry ejaculation
  • Reduced libido or sexual function
  • Small or soft testicles
  • History of infections, injury, or surgery
  • Family history of infertility or genetic issues
symptoms of male infertility

Diagnosis of Azoospermia at Sparsh IVF

Azoospermia requires precise, layered testing to uncover the cause and determine the best course of action:

  • Conducted twice, after 2–5 days of abstinence
  • Confirmed under microscope to detect true absence
  • FSH, LH, Testosterone, Prolactin, TSH
  • Distinguishes between NOA and hormonal dysfunction
  • Checks for blockages or abnormalities in ducts and seminal vesicles
  • Karyotyping and Y-chromosome microdeletion test
  • CFTR mutation analysis for vasal agenesis
  • Especially in NOA cases to assess or retrieve sperm

Our team handles this process with absolute confidentiality and sensitivity.

Treatment Options for Azoospermia

Treatment depends on the type, severity, and cause of azoospermia:

1. Surgical Correction

  • Vasovasostomy (vasectomy reversal)
  • Removal of ejaculatory duct cysts or scar tissue

2. Surgical Sperm Retrieval

  • PESA (Percutaneous Epididymal Sperm Aspiration)
  • TESA (Testicular Sperm Aspiration)
  • MESA (Microsurgical Epididymal Sperm Aspiration)

→ Sperm retrieved is used for IVF-ICSI, not IUI.

1. Medical Management

  • Hormone therapy in selected cases (e.g., hypogonadotropic hypogonadism)

2. Micro TESE (Microsurgical Testicular Sperm Extraction)

  • High-precision procedure using an operating microscope
  • Identifies small regions of active sperm production
  • Performed under anesthesia with minimal tissue damage
  • Sperm frozen for use in IVF-ICSI

Success depends on testicular histology and hormonal profile, but many NOA patients have achieved biological fatherhood with Micro TESE + ICSI.

We offer:

  • Donor Sperm IVF: A respectful, confidential process
  • Counselling and psychological support
  • Opportunity to build a family through reliable and ethical third-party reproduction
IVF Process In Udaipur India

IVF with Azoospermia — Our Expertise

Sparsh IVF has helped hundreds of azoospermic men become fathers through:

  • State-of-the-art Micro TESE and ICSI protocols
  • In-house andrology and embryology labs
  • Transparent counselling on expectations and options
  • Sperm freezing and embryo banking for future planning

Even one viable sperm can be enough with our expertise and your trust.

Why Choose Sparsh IVF?

  • One of the few centers offering in-house surgical sperm retrieval
  • Expert embryologists for ICSI success with limited sperm
  • Clear diagnosis to avoid unnecessary procedures
  • Seamless coordination between urologists and fertility experts
  • Discreet, confidential, and compassionate care
Latest IVF Technologies in Udaipur india

Zero Sperm Is Not the End of Your Story

At Sparsh IVF, we don’t stop at the diagnosis. We look deeper, think smarter, and work harder to uncover every possible solution. Azoospermia is a challenge — not a conclusion.

Book your confidential male fertility consultation today. With modern science and skilled hands, fatherhood is within reach.

There may be no sperm in the sample — but there’s still hope in the journey. We help you find it.