Premature Ovarian Insufficiency (POI) and Infertility

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Premature Ovarian Insufficiency (POI) and Infertility

When Ovaries Slow Down Too Soon — But Hope Remains

For many women, the word “menopause” belongs far in the future. But when your ovaries begin to lose function before the age of 40, it could be a condition known as Premature Ovarian Insufficiency (POI). At Sparsh IVF, we understand the shock, grief, and confusion that a POI diagnosis can bring — and we’re here to help navigate the next steps with clarity and compassion.

With the right combination of medical science, fertility support, and emotional care, pregnancy is still possible, even after a POI diagnosis.

What Is Premature Ovarian Insufficiency?

POI — sometimes called early ovarian failure — occurs when the ovaries stop producing normal amounts of estrogen and fail to release eggs regularly before age 40.

It’s important to note:

  • POI is not the same as menopause.
  • Women with POI may still ovulate occasionally and can sometimes conceive naturally — though the chances are reduced.
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Women Care Center in Udaipur India

Causes of POI

In many cases, the exact cause of POI remains unknown. However, known causes include:

  • Genetic conditions (e.g., Turner syndrome, Fragile X)
  • Autoimmune disorders
  • Previous chemotherapy or radiation
  • Surgical removal of ovaries
  • Chromosomal abnormalities
  • Infections like mumps oophoritis
  • Environmental toxins and smoking

Regardless of the cause, what matters most is early diagnosis and personalized fertility planning.

Symptoms of POI

Some women discover POI while investigating irregular cycles or difficulty getting pregnant. Others experience more sudden signs:

  • Irregular or missed periods
  • Hot flashes and night sweats
  • Mood swings or irritability
  • Decreased libido
  • Vaginal dryness
  • Difficulty conceiving
  • Family history of early menopause

At Sparsh IVF, we approach POI with sensitivity — ensuring patients feel supported through what is often a deeply emotional diagnosis.

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Laparoscopy for female infertility

Diagnosis of POI at Sparsh IVF

To confirm POI, we conduct a thorough evaluation:

  • AMH (Anti-Müllerian Hormone): Assesses ovarian reserve
  • FSH and LH tests: High levels may indicate diminished ovarian activity
  • Estradiol levels: Helps assess hormonal activity
  • Transvaginal Ultrasound (TVS): To examine follicle count (AFC)
  • Genetic testing: In young patients or those with a family history
  • Thyroid and adrenal evaluation: Rule out autoimmune causes

All diagnostic services are offered in-house, ensuring fast, confidential results and integrated care.

POI and Fertility — What Are Your Options?

Some women with POI still experience occasional ovulation. We may support this with:

  • Ovulation tracking
  • Timed intercourse
  • Low-dose fertility medications

While rare, natural pregnancy is still possible in early or mild POI cases.

  • Ultrasoft stimulation protocols to retrieve any remaining viable eggs
  • IVF with ICSI to maximize fertilization
  • Frozen Embryo Transfer (FET) when lining is optimal

Success rates are lower, but not zero — and Sparsh IVF carefully tailors every protocol to the individual.

When AMH is extremely low or follicles are absent, IVF with donor eggs becomes a highly successful path.

  • High-quality, pre-screened donors
  • Matched by age, blood type, and physical attributes
  • Over 70% success rate in women with POI using donor eggs
  • Full emotional counselling provided before decision-making

This option brings renewed hope — and often, a faster route to successful pregnancy.

In women diagnosed at an early stage of POI, we may offer:

  • Egg freezing (if viable follicles are still present)
  • Embryo freezing with partner or donor sperm
  • Ovarian tissue freezing in rare cases (experimental)

Hormone Replacement Therapy (HRT) and Wellness

Even if pregnancy isn’t the goal, managing POI is important for long-term health. We offer:

  • Customized HRT plans to prevent osteoporosis, heart disease, and mood disorders
  • Nutrition and bone density monitoring
  • Lifestyle counselling
  • Mental health and emotional wellness support
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Best Gynecologist In Udaipur India

Why Choose Sparsh IVF?

  • Expertise in low AMH and POI fertility care
  • Full-spectrum services: diagnosis to IVF under one roof
  • Highly successful donor egg IVF programs in India
  • Honest, ethical conversations — no false promises
  • Compassionate team that understands the emotional weight of this diagnosis

Turning the Page — From Diagnosis to Possibility

Premature ovarian insufficiency may change the timeline — but not your destination. At Sparsh IVF, we walk beside you, empowering you with facts, support, and science-backed fertility options.

Book a consultation with our reproductive experts today — and let’s explore the possibilities, together.

Even when the ovaries quiet down early, the dream of motherhood doesn’t have to fade. At Sparsh IVF, we speak the language of hope, one cycle at a time.